Sky Sports Premier League will host live and exclusive coverage of 20 top-flight matches in October and November.
This will include seven head-to-head matches between teams that finished in the top six last season.
Highlights of the autumn schedule include Liverpool's clash against arch-rivals Manchester United on October 14th.
Liverpool will also face a stern test of their title credentials a week later as they head to White Hart Lane to take on Tottenham Hotspur on October 22nd.
Other standouts of the autumn line-up include Manchester City vs Arsenal on November 5th, while City's visit to Huddersfield Town on November 26th also looks an intriguing fixture.
Sky Sports subscribers will be able to follow the action in greater detail with the next-generation Sky Q service, which offers 124 live Premier League games this season in Ultra HD and with Dolby Atmos sound.
Sky Q users will also be able to use the "Watch From Start" function if they have missed the beginning of a match and want to catch up on what they have missed or easily skip to key moments such as goals and bookings.
Gary Hughes, Head of Football at Sky Sports, commented: "The Sky Sports Premier League channel will continue to follow every team in depth like never before.
"From The Debate and Premier League Prediction shows to Soccer AM, Gillette Soccer Saturday and more – fans will get the whole story."
Sky Sports' full Premier League schedule for October and November is as follows:
Sunday October 1st Everton vs Burnley (2.15pm) Newcastle United vs Liverpool (4.30pm)
Saturday October 14th Liverpool vs Manchester United (12:30pm)
Sunday October 15th Southampton vs Newcastle United (4:00pm)
Monday October 16th Leicester City vs West Bromwich Albion (8:00pm)
Friday October 20th West Ham United vs Brighton & Hove Albion (8.00pm)
Sunday October 22nd Everton vs Arsenal (1.30pm) Tottenham Hotspur vs Liverpool (4:00pm)
Monday October 23rd Chelsea vs Watford (8:00pm)
Saturday October 28th Manchester United vs Tottenham Hotspur (12:30pm)
Sunday October 29th Brighton & Hove Albion vs Southampton (1.30pm) Leicester City vs Everton (4.00pm)
Monday October 30th Burnley vs Newcastle United (8.00pm)
Saturday November 4th Stoke City vs Leicester (12.30pm)
Sunday November 5th Manchester City vs Arsenal (2.15pm) Chelsea vs Manchester United (4.30pm)
Sunday November 19th Arsenal vs Tottenham Hotspur (1.30pm) Watford vs West Ham United (4.00pm)
Monday November 20th Brighton & Hove Albion vs Stoke (8.00pm)
Friday November 24th West Ham United vs Leicester City (8.00pm)
Saturday November 25th Southampton vs Everton (12.30pm)
Sunday November 26th Huddersfield Town vs Manchester City (4.00pm)