BT has revealed more than two million households have signed up to BT Call Protect since the service launched three months ago.
BT Call Protect, which is free to BT broadband customers, diverts unwanted calls to a junk voicemail box and works by analysing large amounts of live data, with rogue numbers identified and added to a blacklist.
The Call Protect service can then proactively divert calls before they reach and irritate a customer.
Customers can also compile their own personal blacklist by either dialling 1572 after receiving the call or by going online.
If the same numbers are added by a significant number of customers, they will also be included on BT's blacklist.
BT believes that since the service launched in January, 65 per cent of nuisance calls have been diverted away from customers.
Figures also showed that customers are ringing 1572 more than 80,000 times a week to add numbers to their personal blacklist, check their voicemail or alter their settings.
BT has now called for more people to sign up for the service, as estimates suggest that if all of its customers did so, about 1.6 billion nuisance calls could be diverted every year.
John Petter, Chief Executive of BT Consumer, commented: "The response to BT Call Protect has been massive.
"Having more than two million customers already using the service is a fantastic achievement in our fight against the companies that pester our customers with millions of nuisance calls."
According to the latest figures from BT, 41 per cent of nuisance calls between March 4th and 11th this year related to accident claims.
Meanwhile, 18.5 per cent were from scammers trying to get people's personal details, while 6.4 per cent of nuisance calls related to PPI.