The current Aviva Premiership leaders take on last year's champions in this weekend's big game, to be shown live on BT Sport.
Unbeaten Bath Rugby - who have won three from three at the start of the 2014-15 campaign - travel to Northampton Saints for a 3:15pm kick-off on Saturday September 27th.
Bath are on cloud nine this week after a sensational dismantling of Leicester Tigers last Saturday.
Mike Ford's side ran in five tries in a 45-0 win, inflicting a heaviest-ever Premiership defeat on Leicester.
The clean sheet was all the more pleasing after Bath shipped 26 points against bottom side London Welsh the previous week.
However, Northampton - who won 35-10 at Newcastle Falcons last time out - are sure to provide a sterner test for the league leaders.
The champions responded well to defeat against London Wasps in Week 2, picking up a try bonus on their recent trip to the north-east.
Jill Mallinder's side will have also have a Franklin's Gardens crowd on their side when they host Bath at the weekend.
BT Sport viewers have two other games to look forward to, starting with London Welsh v Gloucester Rugby at 7:45pm on Friday September 26th.
The newly-promoted Exiles have found life difficult on their top-flight return, claiming just one point in their opening three games.
However, the visit of Gloucester is their most winnable game so far, having faced Exeter Chiefs, Bath and Sale Sharks in the first few weeks.
Gloucester, who have just five points to their name so far in 2014-15, spent the entirety of last season in the lower reaches of the division.
David Humphreys' men lost narrowly to Exeter 25-22 at home last time out, following a win against Sale and a defeat to Northampton.
In the third televised game of the weekend, Exeter take on Harlequins - 26-23 victors over Wasps at the weekend.
The Londoners sit in sixth at present, having won two of their opening matches. Exeter have the same results record, but currently lie fourth having claimed an additional two bonus points.
BT Sport subscribers - and BT broadband customers, who can access BT Sport for free - can watch Exeter v Harlequins at 2pm on Sunday September 28th.